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Table 1 Pfmdr1 and pfatpase6 haplotypes from Paragominas (PRG), Porto Velho (PV) and Manaus (MAN) isolates.

From: Brazilian Plasmodium falciparum isolates: investigation of candidate polymorphisms for artemisinin resistance before introduction of artemisinin-based combination therapy

Gene Haplotypes n (n/locality) % Mutated codons
pfmdr1
(n = 85)
NEF/CD VY 82 (19/PRG, 33/PV, 30/MAN) 97 4
  NEF/SD VY 1 (MAN) 1 3
  Y EY/SNVD 1 (MAN) 1 1
  NEY/SNVD 1 (MAN) 1 0
pfatpase6
(n = 65)
HLLE/AAGNKKSK 24 (6/PRG, 4/PV, 14/MAN) 37 0
  HLLE/AS GNKKSK 23 (11/PRG, 12/MAN) 35 1
  HLV E/AAGNKKSK 3 (PV) 5 1
  HLV E/AS GNKKSK 15 (PV) 23 2
  1. Codon positions: pfmdr1 N86Y, E130K, Y184F, S1034C, N1042 D, V1109I, D1246Y (n = 85); pftapase6 H243Y, L263E, L402V, E431K, A623E, A630 S, G639 D, N683K, K716R, K776N, S769N, K771E (n = 65). The haplotype of 3D7 strain is underlined and the mutated codons are shown in bold characters.