Table 1 Medications licensed and recommended for malaria chemoprophylaxis by various countries
From: The position of mefloquine as a 21st century malaria chemoprophylaxis
Medication approved and available for malaria chemoprophylaxis | United States | Canada | United Kingdom | France | Germany | Switzerland | Japan | Australia |
|---|---|---|---|---|---|---|---|---|
Mefloquine | licensed | licensed | licensed | licensed | licensed | licensed | Licensed but not approved for use in children | Licensed but not approved for use in children <14 years old |
Doxycycline* | for age ≥8 years | for age ≥8 years | for age ≥12 years | for age >8 years | Off Label | for age ≥8 years | - | for age >8 years |
Atovaquone-proguanil | licensed | licensed | licensed | licensed | licensed | licensed | - | licensed |
Primaquine | Only licensed for radical cure but is recommended as primary prophylaxis in CDC guideline | licensed | - not recommended for primary prophylaxis | - | - | not registered for primary prophylaxis | not registered for primary prophylaxis | - |
Proguanil in combination with chloroquine | - | - | licensed | licensed ° | licensed | licensed | - | licensed |