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Table 4 Adverse events interfering with daily activity (% of users)

From: The position of mefloquine as a 21st century malaria chemoprophylaxis

Study Population Mefloquine Doxycycline° Atovaquone Proguanil Chloroquine Proguanil
Phillips 1996 Australian 11.2 6.5 - -
Schlagenhauf 1996 Swiss 11.2 - - -
Barrett 1996 UK 17 - - 16
Steffen 1993 European 13 - - 16
Hogh* 2000 International - - 0.2 2.0
Overbosch* 2001 International 5.0 - 1.0 -
Schlagenhauf 2003 International 10.5 5.9 6.7 12.4
  1. Adapted from Schlagenhauf P [18]
  2. * stopped taking anti-malarials
  3. ° more AE with hyclate than monohydrate