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Table 5 Incidence of SERIOUS# Adverse Events during Chemoprophylaxis

From: The position of mefloquine as a 21st century malaria chemoprophylaxis

Report

Population

Mefloquine

Doxycycline

Atovaquone

Proguanil

Chloroquine

Proguanil

MacPhearson 1992

Canadian

1/20,000

?

?

-

Steffen 1993

European

1/11,000

?

?

1/5000

Croft 1996

UK soldiers

1/6,000

?

?

-

Barrett 1996

UK

1/600

?

?

1/1200

Roche Drug Safety 1997

Worldwide

1/20,000

?

?

-

  1. Adapted from Schlagenhauf P [18]
  2. # Hospitalization