Table 6 Adverse event (AE) profile according to age (System Organ Class as a percentage of total reported AE*)
From: The position of mefloquine as a 21st century malaria chemoprophylaxis
No-SOC Abbrev | INFANT (n = 35) (>1 mth - 2 yrs) | CHILD (n = 212) (>2 yrs - 12 yrs) | ADOLESCENT (n = 233) (>12 yrs - 17 yrs) | ADULT (n = 9896) (>17 yrs - 65 yrs) | ELDERLY (n = 451) (over 65 yrs) |
|---|---|---|---|---|---|
01-INFEC-Total | 20.00 | 8.00 | 4.30 | 2.34 | 4.65 |
03-BLOOD-Total | 5.70 | 4.70 | 3.40 | 1.77 | 3.76 |
04-IMMUN-Total | 5.70 | 0.47 | 0.86 | 0.45 | 0.22 |
05-ENDO-Total | 0.00 | 0.47 | 0.00 | 0.16 | 0.22 |
06-METAB-Total | 0.00 | 3.00 | 4.29 | 2.78 | 6,2 |
07-PSYCH-Total | 8.50 | 32.50 | 40.30 | 39.48 | 31.04 |
08-NERV-Total | 17.10 | 27.30 | 39.48 | 35.08 | 35.90 |
09-EYE-Total | 2.86 | 5.18 | 6.86 | 6.05 | 4.65 |
10-EAR-Total | 0.00 | 5.18 | 6.43 | 6.55 | 7.09 |
11-CARD-Total | 5.70 | 3.70 | 3.86 | 7.21 | 10.64 |
12-VASC-Total | 2.86 | 1.40 | 2.14 | 2.67 | 4.65 |
13-RESP-Total | 17.10 | 2.30 | 5.15 | 4.04 | 7.09 |
14-GASTR-Total | 40 | 25.00 | 29.18 | 22.84 | 29.49 |
15-HEPAT-Total | 0.00 | 0.94 | 1.28 | 1.00 | 2.66 |
16-SKIN-Total | 14.28 | 16.98 | 12.87 | 12.42 | 15.52 |
17-MUSC-Total | 0.00 | 2.83 | 7.72 | 5.66 | 8.65 |
18-RENAL-Total | 0.00 | 2.83 | 1.28 | 1.18 | 3.99 |
19-PREG-Total | 0.00 | 0.00 | 0.86 | 15.05 | 0.00 |
20-REPRO-Total | 0.00 | 0.00 | 2.15 | 1.70 | 0.66 |
21-CONG-Total | 2.86 | 0.00 | 0.00 | 0.92 | 0.22 |
22-GENRL-Total | 31.42 | 25.0 | 18.88 | 19.64 | 20.18 |
23-INV-Total | 8.50 | 6.60 | 7.30 | 4.78 | 8.86 |
24-INJ&P-Total | 14.28 | 7.50 | 1.72 | 1.23 | 3.54 |
26-SOCCI-Total | 0.00 | 0.00 | 0.43 | 2.13 | 0.00 |
02-NEOPL-Total | 0.00 | 0.00 | 0.00 | 0.23 | 0.44 |
25-SURG -Total | 0.00 | 0.00 | 0.00 | 0.18 | 0.00 |
Total | 100% | 100% | 100% | 100% | 100% |