Immunological consequences of intermittent preventive treatment against malaria in Senegalese preschool children

Malaria Journal

Table 1 Multivariate mixed-effect regression model of anti-schizont IgG by treatment group.

Variables	Period	Estimates	P-value	95% Confidence interval
Treatment group	2002	0.112	0.379	-0.137	0.360
Gender	-	-0.031	0.787	-0.255	0.193
Age class
3 years (y)	2003	0.410	0.036	0.027	0.793
4 y	2003	0.733	< 0.0001	0.375	1.091
5 y	2003	0.919	< 0.0001	0.530	1.308
6 y	2003	1.035	< 0.0001	0.631	1.439
Stunting	November 2002	0.043	0.814	-0.315	0.401
	July 2003	-0.253	0.144	-0.592	0.086
Wasting	November 2002	0.017	0.933	-0.393	0.428
	July 2003	-0.011	0.963	-0.492	0.469
Malaria morbidity	2002	0.243	0.034	0.018	0.468
Parasitaemia	December 2002	0.573	< 0.0001	0.308	0.839
	July 2003	0.931	< 0.0001	0.653	1.210
Haemoglobin	July 2003	0.003	0.936	-0.082	0.089
Constant term	-	-1.330	0.005	-2.257	-0.404
Random-effects parameters
Village	-	0.244	-	0.114	0.520
Residual	-	0.884	-	0.807	0.969

Gender, age, nutritionnal status and malaria indicators were evaluated as potentially confounding factors, village as a random factor. P values were considered as significant when < 0.05.

ISSN: 1475-2875