Table 2 Outcome variables by treatment assignment
From: Pentoxifylline as an adjunct therapy in children with cerebral malaria
PTX | Control | p | |
|---|---|---|---|
All subjects | (N = 10) | (N = 5) | |
Serious adverse events | 2 (20%) | 0 (0%) | 0.52 |
Seizures during stay | 4 (40%) | 4 (80%) | 0.28 |
Deaths | 4 (40%) | 1 (20%) | 0.60 |
Time to death (hours) | 35 (8 - 54) | 10 | - |
Among survivors | (N = 6) | (N = 4) | |
Parasite clearance time (hours) | 43 ± 9 | 31 ± 8 | 0.05 |
Fever resolution time (hours) | 29 ± 17 | 17 ± 10 | 0.28 |
Coma resolution time (hours)* | 8 (4 - 36) | 8 (4 - 12) | 0.69 |
Duration of hospitalization (days) | 3 (3 - 17) | 4 (3 - 15) | 0.52 |
Neurological impairment after 72 hours | 1 (17%) | 2 (50%) | 0.50 |
Neurological sequelae at 3 months | 0 (0%) | 1 (25%) | 0.40 |