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Table 1 Insecticide resistant and susceptible strains used in the isogenic strain experiment.

From: Insecticide resistance and malaria transmission: infection rate and oocyst burden in Culex pipiens mosquitoes infected with Plasmodium relictum

Strain IR mechanism Alleles Genetic background
SLAB None Ester0, ace-1S SLAB
SA2B2 Overproduction of esterases A2 and B2 Ester2, ace-1S SLAB
SA4B4 Overproduction of esterases A4 and B4 Ester4, ace-1S SLAB
SR Insensitive acetylcholinesterase Ester0, ace-1R SLAB
  1. The overproduction of esterases is controlled by a superlocus consisting of two loci (esterase A and esterase B) in complete linkage disequilibrium. Alleles for this locus are the wild type susceptible Ester0, or the insecticide resistant Ester2 (overproduces the esterase A2 and B2 isozymes) and Ester4 (overproduces the esterase A4 and B4 isozymes). The modification of the acetylcholinesterase is controlled by the locus ace- 1. Alleles for this locus are the wild type susceptible ace-1S and the insecticide resistant ace-1R (which contains a single GGC→AGC point mutation that renders the acetylcholinesterase insensitive to the insecticide). For more details on those strains, see [4].