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Table 1 Physiochemical properties of the 4-position library

From: Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols

Parameter* Range
MW 335-552
LogD -1.2-6.9
PSA 36-111
LogP -2.2-7.1
FRBs 3-12
HBDs 1-5
HBAs 3-8
LVs 0-1
  1. * MW is molecular weight, PSA = polar surface area, FRBs = freely rotatable bonds, HBDs = H-bond donors, HBAs = H bond acceptors and LVs = Lipinski violations.