Evaluation of chloroquine therapy for vivax and falciparum malaria in southern Sumatra, western Indonesia

Malaria Journal

Table 3 Life table estimation of cumulative incidence of chloroquine resistance in P. vivax

Day	N	I	W	IR	CIR	95% Confidence Interval
0	31	0	0	0	0	----
2	31	1	0	0.0333	0.0323	0.0046 - 0.2077
3	30	0	0	0	0.0323	0.0046 - 0.2077
7	30	3	2	0.1034	0.1324	0.0518 - 0.3153
14	25	4	0	0.16	0.2712	0.1457 - 0.4703
21	21	4	6	0.2222	0.4331	0.2715 - 0.6384
28	11	0	3	0	0.4331	0.2715 - 0.6384

D = Day of the test
N = number of subjects remaining at risk
I = incident of resistant cases
W = withdrawals due to intercurrent parasitaemia by P. falciparum or loss to follow up or
parasitaemia positive with CQ level < 100 ng/mL
IR = Interval risk (i{N-(w/2)}^-1
CIR_n = cumulative incidence of resistant case
= 1-(1-IR_n × 1-CIR_n-1) where n is day of test and n-1 is the prior interval, w.g. for calculating CIR day 14, use IR day 14 and CIR day 7

ISSN: 1475-2875