Table 1 Treatment regimens and time of study in the children enrolled
From: Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children
Drugs* | Regimens†| No of patients | Year |
|---|---|---|---|
AQ | 30 mg/kg of amodiaquine base over 3 days, that is, 10 mg/kg daily | 573 | 2000-2006 |
AQAS | Artesunate given as 4 mg/kg dail for 3 d plus amodiaquine given as in AQ above | 142 | 2004-2005 |
AQPS | Amodiaquine given as in AQ above plus sulphadoxine-pyrimethamine given as 25 mg/kg of the sulphadoxine component at presentation | 69 | 2000 |
AQSP | Amodiaquine given as in AQ above plus sulphalene-pyrimethamine given as 25 mg/kg of the sulphalene component at presentation | 91 | 2006 |
AMQ | Mefloquine given as 25 mg/kg at presentation plus artesunate as given in AQAS above | 174 | 2007-2008 |
AL | Artemether (20 mg) plus lumefantrine (120 mg) given thus: 5-14 kg received 1 tab., 15-24 kg received 2 tab., 25-34 kg received 3 tab., > 34 kg received4 tab. at presentation, 8 h later and at 24, 36, 48 and 60 h after first dose | 90 | 2006 |
AS | Artesunate given as 28 mg/kg over 7 days, that is, 4 mg/kg daily | 120 | 2006 |
COT | Co-trimoxazole given as 20 mg of the sulphamethoxazole component twice daily | 104 | 1998-1999 |
CQ | 30 mg/kg of chloroquine base over 3 days, that is, 10 mg/kg daily | 388 | 1996-2004 |
CQCP | 30 mg/kg of chloroquine base over 3 days, that is, 10 mg/kg daily plus chlorpheniramine 8 mg start and 4 mg 8 hourly for 5 d. | 315 | 1996-1999 |
CQKET | 30 mg/kg of CQ base over 3 days, i.e., 10 mg/kg daily plus ketotifen 25 mg/kg statim, followed by 0.125 mg/kg 8 hourly for 4 d. | 70 | 2001 |
CQPS | 30 mg/kg of amodiaquine base over 3 days, that is, 10 mg/kg daily plus sulphadoxine-pyrimethamine given as 25 mg/kg of the sulphadoxine component at presentation | 107 | 2000/2004 |
MQ | Mefloquine given as 25 mg/kg at presentation | 176 | 2007-2008 |
SP | Pyrimethamine-sulphadoxine given as 25 mg/kg of the sulphadoxine component at presentation | 291 | 1996-2004 |
SPP | Sulphadoxine-pyrimethamine given as in PS above plus probenecid at 20-25 mg/kg in two divided doses daily for 3 day | 42 | 2004 |