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Table 1 Treatment regimens and time of study in the children enrolled

From: Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children

Drugs* Regimens† No of patients Year
AQ 30 mg/kg of amodiaquine base over 3 days, that is, 10 mg/kg daily 573 2000-2006
AQAS Artesunate given as 4 mg/kg dail for 3 d plus amodiaquine given as in AQ above 142 2004-2005
AQPS Amodiaquine given as in AQ above plus sulphadoxine-pyrimethamine given as 25 mg/kg of the sulphadoxine component at presentation 69 2000
AQSP Amodiaquine given as in AQ above plus sulphalene-pyrimethamine given as 25 mg/kg of the sulphalene component at presentation 91 2006
AMQ Mefloquine given as 25 mg/kg at presentation plus artesunate as given in AQAS above 174 2007-2008
AL Artemether (20 mg) plus lumefantrine (120 mg) given thus: 5-14 kg received 1 tab., 15-24 kg received 2 tab., 25-34 kg received 3 tab., > 34 kg received4 tab. at presentation, 8 h later and at 24, 36, 48 and 60 h after first dose 90 2006
AS Artesunate given as 28 mg/kg over 7 days, that is, 4 mg/kg daily 120 2006
COT Co-trimoxazole given as 20 mg of the sulphamethoxazole component twice daily 104 1998-1999
CQ 30 mg/kg of chloroquine base over 3 days, that is, 10 mg/kg daily 388 1996-2004
CQCP 30 mg/kg of chloroquine base over 3 days, that is, 10 mg/kg daily plus chlorpheniramine 8 mg start and 4 mg 8 hourly for 5 d. 315 1996-1999
CQKET 30 mg/kg of CQ base over 3 days, i.e., 10 mg/kg daily plus ketotifen 25 mg/kg statim, followed by 0.125 mg/kg 8 hourly for 4 d. 70 2001
CQPS 30 mg/kg of amodiaquine base over 3 days, that is, 10 mg/kg daily plus sulphadoxine-pyrimethamine given as 25 mg/kg of the sulphadoxine component at presentation 107 2000/2004
MQ Mefloquine given as 25 mg/kg at presentation 176 2007-2008
SP Pyrimethamine-sulphadoxine given as 25 mg/kg of the sulphadoxine component at presentation 291 1996-2004
SPP Sulphadoxine-pyrimethamine given as in PS above plus probenecid at 20-25 mg/kg in two divided doses daily for 3 day 42 2004
  1. † All drugs were administered orally. AQ, amodiaquine; AQART, amodiaquine plus artesunate; AQPS, amodiaquine plus pyrimethamine-sulphadoxine; AQSP, amodiaquine-sulphalene-pyrimethamine; ARTMF, mefloquine plus artesunate; ARTMLUM, artemether plus lumefantrine; AS, artesunate; COT, cotrimoxazole; CQ, chloroquine; CQCP, chloroquine plus chlorpheniramine; CQKET, chloroquine plus ketotifine; CQPS, chloroquine plus pyrimethamine-sulphadoxine; MQ, mefloquine; PS, pyrimethamine-sulphadoxine; PSP, pyrimethamine-sulphadoxine plus probenecid;