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Table 4 Predictors of delay in parasite clearance on day 1 after treatment in children with acute falciparum malaria

From: Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children

Variables Number enrolled PC >2 d Crude OR (95% CI) P Value Adjusted OR (95% CI) P Value
Axillary temperature (°C)       
   <38.0 2326 1012 1   1  
   ≥ 38.0 228 139 2.02 (1.53 -2.67) <0.0001 1.80 (1.30-2.50) < 0.001
Parasitaemia (/μl blood)       
≤ 20,000 1328 463 1   1  
>20,000 683 467 5.25 (4.20 - 6.48) <0.0001 5.13 (4.14 - 6.35) < 0.001
Drug treatment *       
CQ 388 275 1 1 1  
AQ 573 298 0.44 (0.33 - 0.58) <0.0001 0.79 (0.63 - 0.98) < 0.03
AQAS 142 14 0.05 (0.03 - 0.08) <0.0001 0.24 (0.10 - 0.57) < 0.0001
AQPS 69 26 0.24 (0.14 - 0.42) <0.0001 0.44 (0.26 - 0.73) 0.002
AQSP 91 34 0.25 (0.15 - 0.39) <0.0001 0.43 (0.29 - 0.68) < 0.0001
AMQ 174 10 0.03 (0.01 - 0.05) <0.0001 0.04 (0.02 - 0.09) < 0.0001
AL 90 6 0.03 (0.01 - 0.07) <0.0001 0.05 (0.02 - 0.12) < 0.0001
AS 120 3 0.01 (0.00 - 0.03) <0.0001 0.02 (0.00 - 0.06) < 0.0001
COT 104 61 0.58 (0.37 - 0.91) 0.017 1.03 (0.68 - 1.36) 0.877
CQCP 315 189 0.61 (0.45 - 0.84) 0.002 1.09 (0.83 - 1.42) 0.512
CQKET 70 36 0.43 (0.25 - 0.73) 0.001 0.77 (0.47 - 1.25) 0.029
CQPS 107 46 0.31 (0.19 - 0.48) <0.0001 0.54 (0.36 - 0.82) 0.004
MQ 176 40 0.12 (0.08 - 0.18) <0.0001 0.21 (0.15 - 0.31) < 0.0001
SP 291 186 0.72 (0.52 - 1.00) 0.055 - -
SPP 42 13 0.18 (0.09 - 0.37) <0.0001 0.33 (0.17 -0.98) 0.001
  1. CI, confidence interval; OR, odd ratio; PC, parasite clearance
  2. * Values of OR represent chances of delay in parasite clearance