Gene | n | Genotype/Haplotype | Prevalence | ||
---|---|---|---|---|---|
 |  |  |  | 1999 | 2007 |
pfcrt Amino acids: 72 - 76 | 64 (1999) | CVMNK | wild-type | 5 (8%) | 1 (17%) |
 | 6 (2007) | CVIET | mutant | 45 (70%) | 5 (83%) |
 |  | CVMNK/CVIET | mixed | 14 (22%) | 0 (0%) |
pfmdr1 Amino acids: 86,184,103, 1042, 1246. | 51 (1999) | 86N | wild-type | 12 (24%) | 4 (67%) |
 | 6 (2007) | 86Y | mutant | 37 (73%) | 2 (33%) |
 |  | 86F | mutant | 2 (4%) | 0 (0%) |
 | 50 (1999) | 184Y | wild-type | 39 (78%) | 2 (33%) |
 | 6 (2007) | 184F | mutant | 11 (22%) | 4 (67%) |
 | 51 (1999) | 1246D | wild-type | 25 (51%) | 6 (100%) |
 | 6 (2007) | 1246Y | mutant | 25 (49%) | 0 (0%) |
 | 50 (1999) | NYD | wild-type | 2 (4%) | 0 (0%) |
 | 6 (2007) | NF D | single-mutant 1 | 4 (8%) | 4 (67%) |
 |  | F YD | single-mutant 2 | 2 (4%) | 0 (0%) |
 |  | NYY | single-mutant 3 | 1 (2%) | 0 (0%) |
 |  | Y YD | single-mutant 4 | 15(30%) | 2 (33%) |
 |  | Y YY | double-mutant 1 | 19 (38%) | 0 (0%) |
 |  | NFY | double-mutant 2 | 4(8%) | 0(0%) |
 |  | YF D | double-mutant 3 | 2(4%) | 0 (0%) |
 |  | YFY | triple-mutant | 1 (2%) | 0 (0%) |
pfdhfr Amino acids: 50,51,59,108,164 | 34 (1999) | CNCSI | wild-type | 3 (8%) | 1 (17%) |
 | 6 (2007) | CNCSI/CIRN I | mixed | 0 (0%) | 1 (17%) |
 |  | CIRN I | triple-mutant | 28 (82%) | 3 (50%) |
 |  | CIRN I/CIRNL | mixed | 0 (0%) | 1 (17%) |
 |  | CIRN I/CI CN I | mixed | 3 (10%) | 0 (0%) |
Pfdhps Amino acids: 436, 437, 540, 581,613. | 27 (1999) | SAKAA | wild-type | 25 (93%) | 6 (100%) |
 | 6 (2007) | SGE AA | double-mutant | 2 (7%) | 0 (0%) |
pfdhr & pfdhps | 23 (1999) | CNCSI/SAKAA | Â | 3 (13%) | 1 (17%) |
 | 6 (2007) | CIRN I/SAKAA |  | 18 (78%) | 5(83%) |
 |  | CIRN I/SGE AA | quintuple-mutant | 2 (9%) | 0 (0%) |