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Figure 2 | Malaria Journal

Figure 2

From: Suppressive effect of azithromycin on Plasmodium berghei mosquito stage development and apicoplast replication

Figure 2

Effect of AZM on P. berghei mosquito stage development. Mosquitoes were allowed to feed on blood of P. berghei-infected mice that had been given AZM (White circle) or CMC (Black circle) at 24 hours before blood feeding. (A) Ookinete numbers in midguts dissected at 24 hours post blood feeding were determined by microscopy analysis. (B) Oocyst numbers on midguts dissected at 10 days post blood feeding were counted. (C, D) Sporozoite numbers in midgut oocysts (C) and salivary glands (D) were determined at 20 days post blood feeding. Horizontal lines and adjacent numbers represent the medians (n = 40 in (A); n = 60 in (B); n = 15 (calculated from 150 mosquitoes) in (C) and (D)). P values were determined by Mann-Whitney U test. Combined results of three to five independent experiments are shown.

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