Figure 2

Diagrammatical representation of pfcrt allele carriage among trial participants during follow-up. Colours represent alleles carried - green for CVMNK and orange for CVIET. White cells indicate PCR was performed but no pfcrt DNA was detected. Shaded cells indicate no sample was taken/available. The SVMNT allele was not detected. Data collected were from single-tube assays of all available DNA samples from each participant (N = 318 data points). A number of individuals without symptoms at Day 3 and with no parasites on initial slide-reading were later found to have harboured parasites by definitive microscopy after completion of the trial. These individuals therefore contributed both Day 3 and Day 7 samples to the analysis, despite being classified ETF.