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Figure 6 | Malaria Journal

Figure 6

From: Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasion

Figure 6

Inhibition of parasite growth by rabbit αMSP-1 antibodies. (A) Immunogenicity of MSP-142, MSP-142ΔEGF and MSP-119 in rabbits. Endpoint titers were determined by ELISA against the whole of MSP-1 (in the form of the p83/30+p38/42 heterodimer), MSP-142, MSP-142ΔEGF, MSP-133, or MSP-119 as shown. For the αMSP-119 antibodies the reciprocal titer directed against GST was 22910 +/- 890 (not shown). Error bars show standard deviations. (B) Growth of P. falciparum strain 3D7 was monitored in the presence of the indicated antibodies at concentrations ranging from 3.125 to 25% (v/v). Pre-immune antibody (25% v/v) was used as a control. Growth inhibition is presented as percent of control. Error bars show standard deviations.

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Malaria Journal

ISSN: 1475-2875

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