Effect of P. berghei infection on GRP78 protein expression in the liver of DBA-2 mice. Immunoblot analysis - with a polyclonal antibody against GRP78 - of liver microsomes from female DBA-2 mice infected with P. berghei (Malaria) on PID20, non-infected controls (Control) and non-infected mice treated with pyrazole (Pyrazole), 100 mg/kg body wt i.p. Densitometric analysis is shown in the lower panel. Height of histogram bars are means ± S.D. of arbitrary optical density units. Difference from non-infected control group is indicated by an asterisk (*, P < 0.05, Mann-Whitney U test). 50 μg of microsomal protein from a different mouse was applied on each lane. The immonoblot shown in the figure is representative of others with similar results.