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Table 1 Association between parasitaemia level, total and functional category scores and the risk of CM development.

From: Algorithms to predict cerebral malaria in murine models using the SHIRPA protocol

Score

Day 4

Day 5

Day 6

 

OR

p-value

95% CI

OR

p-value

95% CI

OR

p-value

95% CI

Parasitaemia

1.250

*0.048

1.002-1.560

1.080

*0.010

1.018-1.145

1.093

*0.001

1.039-1.151

Total

1.042

0.371

0.952-1.141

0.910

*0.003

0.855-0.969

0.907

* < 0.001

0.858-0.958

Reflex

0.978

0.941

0.548-1.746

0.928

0.682

0.650-1.325

0.491

* < 0.001

0.330-0.730

Neuro

0.981

0.923

0.669-1.438

0.719

*0.031

0.532-0.970

0.644

*0.001

0.495-0.839

Motor

1.000

0.998

0.892-1.122

0.833

*0.001

0.749-0.926

0.829

* < 0.001

0.747-0.920

Auto

1.186

0.299

0.859-1.638

0.932

0.393

0.793-1.095

0.883

0.185

0.735-1.061

Muscle

0.352

0.114

0.096-1.287

0.764

0.429

0.393-1.488

0.304

*0.001

0.148-0.621

  1. Association between parasitaemia level, total and functional category scores based on the first screen of SHIRPA protocol on days 4-6 of infection and the risk of CM development in C57Bl/6 mice infected with P. berghei ANKA. OR = Odds Ratio; 95% CI = 95% Confidence Interval for odds ratio. *Denotes statistical significance in this table.