Table 4 Structure-based comparison with hSET mutagenesis data of residues which effect binding (completely or partially) to histones

1

S162

D192

E161

Q150

D278

2*

K164

K194

K163

D152

H281

3

D165

N195

N164

S153

N282

4

T191

H227

E187

G181

N314

5*

T194

T230

T190

R184

D317

6

D195 (disordered)

S231

T191

W185

D317

7

D202

Y259

P198

D198

Y342

8*

E203

E260

D199

S199

S343

9*

E206

L263

E202

S202

E246

10*

K209

K266

R205

S205

K349

11

D210

E267

R206

E206

D350

12*

D211

R268

E207

E207

K351

13

E187 (disordered)

D223

W183

K177

E320