Table 1 Baseline characteristics of patients, according to treatment group.

Age (years)

Median (Range)

32(15-74)

32.5(15-77)

0.33

Sex - Male/Female

133/53

142/42

0.21

Previous treated with quinine for current malaria contracted: no. of patients (%)

11(5.9)

15(8.2)

0.4

Previously treated with artemisinin derivatives for current malaria episode: no. of patients (%)

114(61.3)

105(57.1)

0.41

Convulsions: no. of patients (%)

13(7.0)

14(7.6)

0.82

Temperature (°C)

Median (Range)

38.1(36.5-40.5)

38.0(36.0-41.0)

0.75

Pulse (rate/min)

Median (Range)

100 (68-150)

100 (60-151)

0.30

Respiratory rate (/min)

Median (Range)

28 (12-60)

28 (18-68)

0.27

Glasgow Coma Score

Median (Range)

11 (3-15)

11 (3-15)

0.61

Glasgow Coma score less than 11: no. of patients (%)

85(45.7)

87(47.3)

0.76

Shock: no. of patients (%)

6(3.2)

10(5.4)

0.30

Hypoglycaemia: no. of patients (%)

1(0.5)

0(0)

1.0

Haematocrit (%)

Median (Range)

32 (10-50)

31 (8-53)

0.42

Parasite count (×10³/mm³)

Median (Range)

80.7(0.02-3471)

70.5 (0.02-3534)

0.75

White cell count (×10³/mm³)

Median (Range)

173/171

7.93 (1.1-47.6)

8.40 (1.7-27.0)

0.45

Serum creatinine (mg/dL)

Median (Range)

179/176

1.8 (0.6-9.5)

1.7 (0.6-17.0)

0.68

Total bilirubin (mg/dL)

Median (Range)

124/120

5.7 (0.6-39.0)

5.0 (0.6-38.8)

0.40

ALT (U/L)

Median (Range)

155/161

70 (10-1900)

71 (6-414)

0.45

Lactate (mmol/L)

Median (Range)

168/166

3.2 (0.5-17.7)

3.6 (0.5-16.8)

0.85