Table 2 Outcomes after treatment with intramuscular artesunate or artemether.
Outcomes | ARTS n = 186 | ARTM n = 184 | Relative Risk (95% CI) | P value |
|---|---|---|---|---|
Mortality (%) | 13(7.0) | 24(13.0) | 0.54(0.28-1.02) | 0.052 |
Convulsions (n) | 7(3.8) | 9(4.9) | 0.77(0.29-2.02) | 0.59 |
Required blood transfusion (%) | 69(37.1) | 69(37.5) | 0.99(0.76-1.29) | 0.94 |
Renal impairment (%) | 111(59.7) | 105(57.1) | 1.05(0.88-1.24) | 0.61 |
Renal failure (%) | 85(45.7) | 85(46.2) | 0.99(0.79-1.23) | 0.92 |
Required dialysis (%) | 52(28) | 54(29.3) | 0.95(0.69-1.31) | 0.77 |
Hypoglycaemia (%) | 7(3.8) | 9(4.9) | 0.77(0.29-2.02) | 0.59 |
Spontaneous bleeding (%) | 26(14) | 35(19) | 0.73(0.46-1.17) | 0.19 |
Shock (%) | 22(11.8) | 26(14.1) | 0.84(0.49-1.42) | 0.51 |
Concomitant infection (%) | 66(35.5) | 75(40.8) | 0.87(0.67-1.13) | 0.30 |
Jaundice (%) | 144(77.4) | 144(78.3) | 0.99(0.89-1.1) | 0.85 |
Pulmonary oedema (%) | 10(5.4) | 13(7.1) | 0.76(0.34-1.69) | 0.5 |