Table 3 Multivariate logistic regression analysis of factors associated with death in severe falciparum malaria patients.

IM artesunate treatment

0.41(0.16 - 1.06)

0.066

60 out of 370 were not included (30 in ATS and 30 in ATM) due to missing of lactate and/or WBC count)

Year of study (after 2000)

0.14(0.03 - 0.71)

0.017

Each unit higher in Glasgow Coma score

0.82(0.72 - 0.93)

0.002

Unit increase in admission plasma lactate

1.28(1.15 - 1.43)

< 0.001

Each 10³ WBC/mm³ rise

1.1(1.02 - 1.18)

0.017

Pre-treatment with artemisinin derivatives

0.29(0.11 - 0.82)

0.019