Evaluation of in vivo Antiplasmodial Activities of extracts of Morinda morindiodes (Bak.) in the treatment of malaria in Ogun State

Table 1 Chemosuppression and survival time of P. berghei infected mice treated orally with Morinda morindiodes extracts at a dose of 100mg/kg body weight once a day for 5 days

Plant part	Extract	%chemosuppression of parasitaemia at day 5 (C.P.±S.D)	%chemosuppression of parasitaemia at day 11 (C.P.±S.D)	Mean Survival time (days)
Leaf	MeOH	7.5 ± 2.8^b	82.4±5.6^e	19.5
Water	10±2.8^bc	72.6±8.4^bc	16.5
F.M. starch	7.5 ± 2.8^b	78.8 ± 9.9^d	16.5
Stem	MeOH	0 ± 2.8^a	60.8 ± 5.6^a	16.5
Water	1.3 ± 1.41^ab	72.2 ± 14.8^bc	15.5
F.M. starch	5.0 ± 2.8^b	71.6 ± 0.0^bc	16.5
Root	MeOH	20.5 ± 22.6^bc	67.3 ± 7.07^b	18.5
Water	52.5±2.8^d	76.5 ± 0.0^cd	19.5
F.M. starch	30±8.5^c	79.1 ± 0.0^d	19.5
Chloroquine		100 ± 0.0^e		28.5
Artesunate		100 ± 0.0^e		28.5
Control		0.0		14.5

MeOH, methanol extract; F.M. starch, "aqueous fermented maize starch ('omidun') extract".

ISSN: 1475-2875