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Table 1 IC50 values for inhibition of P. falciparum growth and heme crystallization

From: 2-tert-butyl-primaquine exhibit potent blood schizontocidal antimalarial activity via inhibition of heme crystallization

Drug

IC50 (μM) for inhibition of

 

P. falciparum D6 clone growth

BH formation

CQ

0.3

15.4

PQ

ND*

ND*

BPQ

0.1

2.9

  1. *ND, not detected.
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Malaria Journal

ISSN: 1475-2875

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