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Table 3 PCR-adjusted therapeutic response (per protocol analysis) for day 14 and day 28

From: Randomized non-inferiority and safety trial of dihydroartemisin-piperaquine and artesunate-amodiaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroonian children

 

Day 14

 

Day 28

 

Outcome

AL

ASAQ

DHAP

P-value

AL

ASAQ

DHAP

p-value

ACPR

119

250

236

0.51*

119

243

236

0.78*

ETF

0

0

2

0

0

2

LTF

1

2

4

1

7

4

LPF

3

2

3

3

4

3

  1. ACPR = adequate clinical and parasitological response; ETF = early treatment failure.
  2. LCF = late clinical failure; LPF = late parasitological failure; AL = artemether-lumefantrine; DHAP = dihydroartemisinin-piperaquine; ASAQ = artesunate-amodiaquine; * = Fischer exact test (significant if there is at least one significant difference in therapy outcome level when comparing the three treatment regimen).
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Malaria Journal

ISSN: 1475-2875

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