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Table 2 The calculated percentage of suppression (inhibition) of Plasmodium berghei per dose

From: In vivo antiplasmodial and toxicological effect of Maytenus senegalensis traditionally used in the treatment of malaria in Tanzania

Dose in mg/kg body weight

Calculation of % inhibition of parasitaemia

Percent inhibition

P value of Pos. control vs Tests

25

100 - [6.5/56.53 × 100]

88.50

P < 0.05

50

100 - [3.59/56.53 × 100]

93.65

P < 0.05

75

100 - [1.9/56.53 × 100]

96.64

P > 0.05*

100

100 - [1.1/56.53 × 100]

98.054

P > 0.05*

Negative control

100 - [56.53/56.53 × 100]

0

 

Positive control (SP) (25/1.25

100 - [0.52/56.53 × 100]

99.08

 
  1. *SP (standard drug) has no marked superiority to M. senegalensis extract at a dose of 75-100 mg/kg.