Skip to main content

Table 5 Toxicity effect manifestation of M. senegalensis ethanol extract in experimental mice

From: In vivo antiplasmodial and toxicological effect of Maytenus senegalensis traditionally used in the treatment of malaria in Tanzania

Response

Dosage of extract administered to test mice (mg/kg body weight)

200

300

400

800

1600

Before

After

Before

After

Before

After

Before

After

Before

After

1. Alertness

N

N

N

N

N

N

N

N

N

N

2. Grooming

A

A

A

A

A

A

A

A

A

A

3. Tremors

A

A

A

A

A

A

A

A

A

A

4. Convulsion

A

A

A

A

A

A

A

A

A

A

5. Urination

N

N

N

N

N

N

N

N

N

N

6. Salivation

N

N

N

N

N

N

N

N

N

N

7. Writhing

A

A

A

A

A

A

A

A

A

A

  1. Key: N = normal; A = absent.