Table 4 Comparison of ability to estimate liver to blood inoculum (LBI) using peak method for participants in VAC052 and KCS: qRT-PCR vs Oxford qPCR methods
Study | LBI | Oxford qPCR: n (%) | ||||
|---|---|---|---|---|---|---|
Able to estimate using data ≥ LLQ | Able to estimate using data ≥ LLD | Not able to estimate using data ≥ LLQ | Not able to estimate using data ≥ LLD | |||
VAC052 (n = 27) | UW large volume qRT-PCR: n (%) | Able to estimate using data ≥ LLQ | 18 (67%) | 22 (81%) | 5 (19%) | 1 (4%) |
Not able to estimate using data ≥ LLQ | 0 (0%) | 1 (4%) | 4 (15%) | 3 (11%) | ||
KCS (n = 28) | UW large volume qRT-PCR: n (%) | Able to estimate using data ≥ LLQ | 20 (71%) | 28 (100%) | 8 (29%) | 0 |
Not able to estimate using data ≥ LLQ | 0 | 0 | 0 | 0 | ||