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Table 5 Estimations of liver to blood inoculum (LBI) for KCS study

From: Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies

LBI

Peak method*

≥ LLQ

≥ LLD

Min

Max

Min

Max

Oxford qPCR

97,608**

1,396,941**

33,768

1,396,941

UW large volume qRT-PCR

37,800

1,855,630

37,800

1,855,630

  1. *Units are total number of parasites estimated to be released from the liver.
  2. **n = 20 (8 volunteers had negative LBI). All other analyses n = 28.