Studied polymorphisms
 
Malaria (+) (n = 73)

Malaria (−) (n = 194)

OR (95% CI)

*
P value


IFNG + 874 T/A
     
Genotypes

A/A

38 (52%)

101 (52.1%)

1.00

0.92


A/T

30 (41.1%)

77 (39.7%)

0.97 (0.551.70)


T/T

5 (6.8%)

16 (8.2%)

1.20 (0.413.51)

Alleles

A

106 (73%)

279 (72%)

0.16 (0.68  1.58)

0.87


T

40 (27%)

109 (28%)

NOS2A952G/C
     
Genotypes

G/G

70 (95.9%)

183 (94.3%)

1.00

0.6


G/C

3 (4.1%)

11 (5.7%)

1.40 (0.385.18)


C/C







Alleles

G

143 (98%)

377 (97%)

1.39 (0.38  5.05)

0.6


C

3 (2%)

11 (3%)

IL10A1082G/A
     
Genotypes

A/A

3 (4.1%)

40 (20.6%)

1.00

0.0009


G/A

64 (87.7%)

135 (69.6%)

0.16 (0.050.53)


G/G

6 (8.2%)

19 (9.8%)

0.24 (0.051.05)

Alleles

A

70 (48%)

215 (62%)

0.74 (0.50  1.08)

0.12


G

76 (52%)

173 (45%)

IL10A592A/C
and
IL10A819 T/C
     
Genotypes

C/C

13 (17.8%)

70 (36.1%)

1.00

0.0002


A/C; T/C

36 (49.3%)

100 (51.1%)

0.52 (0.261.04)


A/A; T/T

24 (32.9%)

24 (12.4%)

0.19 (0.080.42)

Alleles

C

62 (42%)

240 (62%)

0.45 (0.30  0.67)

0.0001


A/T

84 (58%)

148 (38%)


IFNG + 874 T/A, NOS2A954G/C, IL10A1082G/A, IL10A592A/C and IL10A819 T/C polymorphisms: Alleles, n (%); Genotypes n (%); OR (95% CI), calculating odds ratios with confidence interval (CI) of 95%; *Analysis by χ^{2} test using the Fisher model codominance.