Figure 3

Parasitaemia patterns for wild-type and piperaquine (PQ)-resistant Plasmodium berghei ANKA parasites treated with PQ at passages 2, 10 and 18. The mice were treated once daily for 3 days with PQ (15 mg/kg cumulative dose) at every two passages. The patterns mirror each other (2, 10 and 18), confirming that the PQ-resistance is stable. No recrudescent parasites were observed following treatment of wild type infected mice, up to D₃₀ post-infection.