Table 3 Diagnostic accuracy of NINA-LAMP and microscopy compared with the gold standard nested PCR for diagnosis of Plasmodium parasite and P. falciparum at Kola Diba Health Centre, Northwest Ethiopia, 2014
Method |  | Senstivity(%) (95% CI) | Specificity(%) (95% CI) | PPV(%) (95% CI) | NPV(%) (95% CI) | %agreement (Kapp = κ ) |
|---|---|---|---|---|---|---|
NINA -LAMP | Pan (Gondar) | 96.8 (83.2-99.5) | 84.3 (71.4-92.9) | 52.1 (33.9-71.3) | 99.3 (96.0-99.9) | 89.0 (0.776) |
| Â | Pf (Gondar) | 100 (75.1-100) | 81.2 (69.9-89.6) | 27.0 (14.8-40.0) | 100 (97.6-100) | 84.1 (0.577) |
| Â | Pan (Calgary) | 96.8 (83.2-99.5) | 98.0 (89.5-99.7) | 89.7 (58.3-98.2) | 99.4 (96.8-99.9) | 97.6 (0.948) |
| Â | Pf (Calgary) | 100 (75.1-100) | 100 (94.7-100) | 100 (49.8-100) | 100 (98.2-100) | 100 (1.000) |
Microscopy | Pan | 93.6 (78.5-99.0) | 98.0 (89.5- 99.7) | 89.4 (56.9-98.2) | 98.8 (95.9-99.8) | 96.3 (0.922) |
| Â | Pf | 92.3 (63.9-98.7) | 100 (94.7-100 ) | 100 (45.8-100) | 99.5 (97.4-99.9) | 98.8 (0.953) |