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Figure 1 | Malaria Journal

Figure 1

From: Transcription of the var genes from a freshly-obtained field isolate of Plasmodium falciparum shows more variable switching patterns than long laboratory-adapted isolates

Figure 1

Subclassification of DBL domains of FCYN0906-5H. a. Distance tree of DBL sequences of FCYN0906-5H generated using the p-distance/NJ method. DBL domains are divided into six major groups and the DBLα branch separated from the other groups. b. Phylogenetic trees of all DBLα amino acid sequences between the laboratory clone (3D7) and the wild isolate(FCYN0906-5H). The var genes of 3D7 are labelled as circles and those of FCYN0906-5H are labelled as triangles. Var gene groups are marked by different colours. Although upsB and upsC sub-groups overlapped, the upsA sub-group could be distinguished from others. Meanwhile, var4 and var84 had no upstream sequences but were assumed to be a sub-type of upsA as they were also within the upsA sub-group.

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