Figure 2From: Protection of Malian children from clinical malaria is associated with recognition of multiple antigens Humoral responses by age at the beginning of the transmission season. Antibody reactivity against P. falciparum antigens was assessed in samples from (n = 99) children collected at baseline. A pool of sera from 100 hyperimmune Tanzanians (HIT) was used as a standard positive control. Reactivity for each antigen in undiluted HIT serum was set at 100 arbitrary units (AU). Humoral reactivity was assessed against (A) AMA-1, (B) MSP-119, (C) MSP-3, (D) CSP and (E) GLURP-R0. Children were divided into three different age groups: two to five years (n = 36), six to nine years (n = 27) and ten to 14 years (n = 36). Responses between the three age groups were compared using Kruskal-Wallis with Dunn’s multiple comparison post-test. *p < 0.05; **p < 0.01; ***p < 0.001. Scatter plots show individual data points, horizontal lines indicate the median of the group and error bars the interquartile range (IQR).Back to article page