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Figure 2 | Malaria Journal

Figure 2

From: Protection of Malian children from clinical malaria is associated with recognition of multiple antigens

Figure 2

Humoral responses by age at the beginning of the transmission season. Antibody reactivity against P. falciparum antigens was assessed in samples from (n = 99) children collected at baseline. A pool of sera from 100 hyperimmune Tanzanians (HIT) was used as a standard positive control. Reactivity for each antigen in undiluted HIT serum was set at 100 arbitrary units (AU). Humoral reactivity was assessed against (A) AMA-1, (B) MSP-119, (C) MSP-3, (D) CSP and (E) GLURP-R0. Children were divided into three different age groups: two to five years (n = 36), six to nine years (n = 27) and ten to 14 years (n = 36). Responses between the three age groups were compared using Kruskal-Wallis with Dunn’s multiple comparison post-test. *p < 0.05; **p < 0.01; ***p < 0.001. Scatter plots show individual data points, horizontal lines indicate the median of the group and error bars the interquartile range (IQR).

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