Figure 1From: A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail Docking results of compounds identified from virtual screening and in vitro inhibition of Pf SpdS. aResults represent the percentage PfSpdS activity inhibited compared to untreated enzyme of three independent experiments performed in duplicate. Data are given as means ± SEMs. bThese compounds were docked in the presence of both MTA and dcAdoMet. NA; not applicable. ND; not determined. *Used as control to verify DPMs. #Atoms predicted to influence binding affinity.Back to article page