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Table 1 Comparisons between the model output and summary statistics for 48 sporozoite-induced infections (drawn from McKenzie et. al. [21])

From: A simulation model of the within-host dynamics of Plasmodium vivax infection

 

Min

Max

Median

Mean

Std dev

Day of 1st parasite peak

14 (5)

32 (34)

18 (10)

19.4 (11.4)

3.0 (5.9)

Peak parasitaemia (/μL)

5567 (693)

53246 (20376)

14939 (8131)

16475 (8675)

6384 (4964)

Day of 1st fever

16 (3)

36 (22)

20 (8)

21.7 (NA)

3.6 (4.1)

Peak fever

0.447

8.336

0.983

1.134

0.574

Day of peak gametocytes

16 (7.5)

38 (29.5)

20 (17)

21 (18.1)

3.8 (6.0)

Peak gametocytemia (/μL)

479 (20)

4939 (840)

1294 (152)

1415 (209)

548 (NA)

  1. Values reported by McKenzie et al. are listed in parentheses where available. Peak fever represents the proportion of parasites in excess of the fever threshold; no equivalent measurements were available from McKenzie et. al. [21]. For the model outputs, Day 0 represents the day the exo-erythrocytic schizont releases merozoites into the host circulation.