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Table 1 Baseline characteristics of all episodes of uncomplicated falciparum malaria treated with AL

From: Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria in the setting of three different chemopreventive regimens

Characteristic

Chemoprevention arm

No chemoprevention

Monthly

Daily

Monthly

SP

TS

DP

Number of episodes

992

901

721

444

Patient age in months, mean (SD)

16.0 (5.1)

16.1 (5.1)

16.9 (4.8)b

17.8 (4.5)b

Female gender, n (%)

428 (43.2%)

407 (45.2%)

344 (47.7%)

211 (47.5%)

Urban residence, n (%)

13 (1.3%)

26 (2.9%)

14 (1.9%)

18 (4.1%)

Household wealth index, n (%)

    

  Lowest tertile

319 (32.2%)

284 (31.5%)

308 (42.7%)b

176 (39.6%)b

  Middle tertile

381 (38.4%)

347 (38.5%)

236 (32.7%)

149 (33.6%)

  Highest tertile

292 (29.4%)

270 (30.0%)

177 (24.6%)

119 (26.8%)

HIV-exposeda, n (%)

235 (23.7%)

179 (19.9%)

114 (15.8%)

81 (18.2%)

Temperature °C, mean (SD)

38.0 (1.0)

37.9 (1.0)

37.9 (1.0)

37.9 (1.0)

Parasite density per μL, geometric mean

16321

15257

11702b

16841

Gametocytes present, n (%)

41 (4.1%)

34 (3.8%)

48 (6.7%)b

11 (2.5%)

Haemoglobin g/dL, mean (SD)

9.7 (1.3)

9.6 (1.4)

9.8 (1.3)

9.9 (1.2)

Days since last dose of chemopreventive drug assigned, median (IQR)

N/A

17 (10–24)

1 (1–1)

16 (8–23)

Proportion of prior dose of chemopreventive drug reported taken

N/A

95.5%

98.6%

96.0%

  1. aHIV-uninfected children born to HIV-infected mothers.
  2. bp-value < 0.05 when compared to no chemoprevention arm.