Table 3 Risk factors associated with recurrent malaria within 84 days following treatment with AL
Risk factor | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
HR a (95% CI) | p-value | HR a (95% CI) | p-value | ||
Chemoprevention arm | No chemoprevention | 1.0 (reference) | - | 1.0 (reference) | - |
Monthly SP | 0.95 (0.81-1.11) | 0.51 | 0.95 (0.81-1.12) | 0.52 | |
Daily TS | 0.87 (0.72-1.05) | 0.14 | 0.85 (0.70-1.05) | 0.07 | |
Monthly DP | 0.81 (0.66-0.99) | 0.04 | 0.77 (0.63-0.95) | 0.01 | |
Age (per 6 month increase) | 1.15 (1.09-1.23) | <0.001 | 1.19 (1.12-1.26) | <0.001 | |
Pre-treatment parasite density (per 1og10 increase) | 1.06 (1.01-1.11) | 0.01 | 1.05 (1.00-1.10) | 0.04 | |
HIV-exposure | 0.91 (0.77-1.08) | 0.27 | 0.86 (0.73-1.02) | 0.09 | |
Female gender | 0.94 (0.82-1.07) | 0.33 | 0.94 (0.82-1.07) | 0.34 | |
Urban residence | 0.57 (0.27-1.20) | 0.14 | 0.65 (0.32-1.33) | 0.23 | |
Household wealth index | Lowest tertile | 1.0 (reference) | - | 1.0 (reference) | - |
Middle tertile | 0.92 (0.79-1.07) | 0.27 | 0.91 (0.78-1.06) | 0.24 | |
Highest tertile | 0.77 (0.65-0.91) | 0.002 | 0.78 (0.66-0.92) | 0.003 | |