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Table 2 Pfcrt haplotypes at the 2007 survey in western Kenya, by study area

From: Assessment of molecular markers for anti-malarial drug resistance after the introduction and scale-up of malaria control interventions in western Kenya

pfcrt haplotype a

72

73

74

75

76

No. mutations

Asembo, N (%)

Gem, N (%)

Karemo, N (%)

(n = 52)

(n = 86)

(n = 89)

Wild type

C tgt

V gta

M atg

N aat

K aaa

    

Mutant

S agt

 

I att

E gaa

T aca

    

S tct

K aaa

 

C

V

M

N

K

0

2 (4)

13 (15)

19 (21)

 

C

V

I

N

K

1

0 (0)

1 (1)

2 (2)

 

C

V

M

E

K

1

0 (0)

1 (1)

0 (0)

 

C

V

M

N

T

1

3 (6)

1 (1)

1 (1)

 

C

V

M

K

T

2

4 (8)

0 (0)

0 (0)

 

C

V

M

E

T

2

1 (2)

0 (0)

3 (3)

 

C

V

I

N

T

2

1 (2)

0 (0)

2 (2)

 

C

V

I

K

K

2

0 (0)

1 (1)

0 (0)

 

C

V

I

E

K

2

1 (2)

0 (0)

1 (1)

 

C

V

I

K

T

3

1 (2)

0 (0)

0 (0)

 

C

V

I

E

T

3

39 (75)

69 (80)

61 (69)

  1. Note. No. = number. Wild type amino acids are shown in normal font, while mutated amino acids are depicted in bold font. aThe construction of the pfcrt haplotype included codons 72, 73, 74, 75, and 76. All isolates coded for wild type C72 and V73.