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Table 3 Pfmdr1 haplotypes at the 2007 survey in western Kenya, by study area

From: Assessment of molecular markers for anti-malarial drug resistance after the introduction and scale-up of malaria control interventions in western Kenya

pfmdr1 haplotype a

86

184

1034

1042

1246

No. mutations

Asembo, N (%)

Gem, N (%)

Karemo, N (%)

(n = 47)

(n = 75)

(n = 70)

Wild type

N aat

Y tat

S agt

N aat

D gat

    

Mutant

Y tat

F ttt

C tgt

D gat

Y tat

    
 

N

Y

S

N

D

0

5 (11)

10 (13)

9 (13)

 

N

Y

S

N

Y

1

2 (4)

8 (11)

2 (3)

 

N

F

S

N

D

1

5 (11)

6 (8)

7 (10)

 

Y

Y

S

N

D

1

16 (34)

20 (27)

22 (31)

 

N

F

S

N

Y

2

1 (2)

3 (4)

1 (1)

 

Y

F

S

N

D

2

2 (4)

6 (8)

7 (10)

 

Y

Y

S

N

Y

2

16 (34)

17 (23)

19 (27)

 

Y

F

S

N

Y

3

0 (0)

5 (7)

3 (4)

  1. Note. No. = number. Wild type amino acids are shown in normal font, while mutated amino acids are depicted in bold font.
  2. a The construction of the pfmdr1 haplotype included codons 86, 184, 1034, 1042, and 1246. All isolates coded for wild type S1034 and N1042.