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Table 1 Ex vivo susceptibility of 18 Plasmodium falciparum isolates from Dakar to chloroquine (CQ), monodesethylamodiaquine (MDAQ), lumefantrine (LMF), dihydroartemisinin (DHA), quinine (QN), mefloquine (MQ), artesunate (AS), pyronardine (PND), piperaquine (PPQ) and Proveblue (PVB)

From: Plasmodium falciparum susceptibility to standard and potential anti-malarial drugs in Dakar, Senegal, during the 2013–2014 malaria season

Drug Isolate IC 50 Resistance or reduced susceptibility
Mean CI 95% Min Max Cut-off %
CQ 52.2 nM 29.1-93.9 6.1 346.4 77 nM 50.0
MDAQ 9.8 nM 5.5-17.4 1.9 117.1 61 nM 5.6
LMF 4.1 nM 2.1-8.1 0.61 82.9 115 nM 0
DHA 0.72 nM 0.35-1.50 0.1 5.08 12 nM 0
AS 1.35 nM 0.53-3.42 0.12 5.53 12 nM 0
QN 63.1 nM 30.9-128.7 6.2 1430 611 nM 5.6
MQ 30.1 nM 19.4-46.6 7.1 63.4 30 nM 55.6
PND 5.8 nM 3.3-10.1 0.4 19.7 ND ND
PPQ 32.2 nM 16.5-62.8 2.5 168.0 ND ND
PVB 5.3 nM 2.8-10.1 0.9 40.2 ND ND
  1. Mean: geometric mean.
  2. CI 95%: 95% confidence interval.
  3. ND: not determined.