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Table 2 Malariometric indices by study village (determined by microscopy and PCR)

From: Epidemiology of forest malaria in Central Vietnam: the hidden parasite reservoir

 

Village 1% (n)

Village 2

Village 3

Village 4

TOTAL % (n/N) [95% CI]

Total screened (by microscopy)

350

256

532

312

1,450

Parasite prevalence (microscopy)

4.9 (17)

3.9 (10)

9.8 (52)

10.9 (34)

7.8 (113/1450)

[6.3; 9.6]°

Prevalence by age group (years):

      

 ≤9

4.7 (6/127)

1.2 (1/84)

9.9 (20/202)

15.4 (18/117)

8.5 (45/530)

[6.3; 11.3] °°

 10–19

7.6 (5/66)

7.6 (4/53)

25.6 (20/78)

11.4 (8/70)

13.9 (37/267)

[9.4; 20.0]

 20–39

4.2 (4/95

5.3 (4/75)

5.6 (9/160)

7.9 (6/76)

5.7 (23/406)

[3.8; 8.3]

 ≥40

3.2 (2/62)

2.3 (1/44)

3.3 (3/92)

4.1 (2/49)

3.2 (8/247)

[1.6; 6.4]

Species distribution (proportion):

      

- P. falciparum

58.8 (10)

80.0 (8)

96.2 (50)

70.6 (24)

81.4 (92)

[72.8; 87.8]°

- P. vivax

41.2 (7)

20.0 (2)

1.9 (1)

29.4 (10)

17.7 (20)

[11.6; 26.1]

- Mixed

0

0

1.9 (1)

0

0.9 (1)

[0.1; 6.3]

Parasite density (geometric mean):

      

 - P. falciparum

1390.9

938.5

2008.3

3007.6

2006.9

[1,523.8; 2,643.1]

 - P. vivax

340.9

423.3

726.6

794.9

559.7

[301.9; 1,037.7]

Infections with gametocytes, % (n)

64.7 (11/17)

40.0 (4/10)

15.4 (8/52)

52.9 (18/34)

36.3 (41/113)

[28.0; 45.5]°°

Proportion asymptomatic, % (n)

76.5 (13/17)

80.0 (8/10)

73.1 (38/52)

58.8 (20/34)

69.9 (79/113)

[60.1; 78.2]

Total surveyed (PCR)

N = 75

N = 55

N = 133

N = 64

N = 327

Parasite prevalence*, % (n)

16.4 (13/75)

18.9 (12/55)

20.2 (25/133)

42.5 (24/64)

23.6 (74/327)

[19.0; 28.9]

Species distribution:

      

P. falciparum (Pf)

25.8 (4)

52.6 (6)

77.5 (17)

58.6 (14)

59.2 (41)

[47.2; 70.2]°

P. vivax (Pv)

74.2 (9)

47.4 (6)

22.5 (8)

37.9 (9)

39.6 (32)

[28.7; 51.6]

Pf + Pv

0

0

0

3.5 (1)

1.2 (1)

[0.2; 8.7]

Prop. sub-patent infections, % (n)

79.0 (10)

73.7 (8)

44.9 (14)

57.2 (14)

58.7 (46)

[46.2; 70.2]

Prop. asymptomatic infections, % (n)

100.0 (13)

71.9 (9)

62.3 (15)

78.6 (18)

75.4 (55)

[63.7; 84.2]

Prevalence ratio LM/PCR

0.30

0.21

0.48

0.26

0.33

 

Mean haemoglobin, g/dl

13.1

13.4

11.9

11.9

12.4

[12.2; 12.6]**

Prevalence anaemia (Hb <10.0 g/dl)

3.4 (2)

2.7 (1)

14.9 (19)

11.7 (7)

9.6 (29)

[6.6; 13.7]°

  1. °Chi-square p < 0.05;
  2. °°Chi-square p < 0.001 (p-values are specified for significant differences between villages for each category);
  3. * Village prevalence was estimated taking into account the survey design (weight = household size; strata = village);
  4. ** Significant Hb decrease by >1.1 g/dl in Villages 3 and 4 compared to Village 1 (svy regress p < 0.05).