G6PD gene variants and its association with malaria in a Sri Lankan population

Malaria Journal

Table 2 Association of the polymorphic SNPs and the malaria infection status

	SNP	Associated Allele	Group A: Group B frequencies	Chi ²	p
Males (n = 426; Group A = 169)	rs766420	G	0.509:0.486	0.206	0.649
	rs915941	C	0.130:0.109	0.444	0.505
	rs915942	G	0.893:0.891	0.006	0.936
	rs2071429	G	0.527:0.420	4.643	0.031
	rs2230037	A	0.479:0.377	4.349	0.037
	rs4898389	G	0.503:0.414	2.991	0.031
	rs5986877	G	0.500:0.415	2.747	0.097
	rs7879049	G	0.436:0.379	1.269	0.260
	rs7053878	T	0.892:0.862	0.790	0.374
Females (n = 464; Group A = 174)	rs766420	G	0.537:0.528	0.083	0.772
	rs915941	A	0.865:0.852	0.310	0.578
	rs915942	G	0.868:0.853	0.370	0.542
	rs2071429	A	0.563:0.557	0.035	0.851
	rs2230037	A	0.405:0.403	0.003	0.958
	rs4898389	A	0.556:0.528	0.607	0.436
	rs5986877	C	0.549:0.524	0.514	0.473
	rs7879049	A	0.608:0.576	0.850	0.356
	rs7053878	T	0.883:0.841	2.847	0.091

Comparison of the genotypes of the 9 polymorphic SNPs with MAF > 10%; frequencies of the associated allele of (Group A)/ (Group B) individuals are also mentioned. Males and females were compared separately using chi squared test.

ISSN: 1475-2875