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Table 2 Association of the polymorphic SNPs and the malaria infection status

From: G6PD gene variants and its association with malaria in a Sri Lankan population

  SNP Associated Allele Group A: Group B frequencies Chi 2 p
Males (n = 426; Group A = 169) rs766420 G 0.509:0.486 0.206 0.649
rs915941 C 0.130:0.109 0.444 0.505
rs915942 G 0.893:0.891 0.006 0.936
rs2071429 G 0.527:0.420 4.643 0.031
rs2230037 A 0.479:0.377 4.349 0.037
  rs4898389 G 0.503:0.414 2.991 0.031
  rs5986877 G 0.500:0.415 2.747 0.097
  rs7879049 G 0.436:0.379 1.269 0.260
  rs7053878 T 0.892:0.862 0.790 0.374
Females (n = 464; Group A = 174) rs766420 G 0.537:0.528 0.083 0.772
rs915941 A 0.865:0.852 0.310 0.578
rs915942 G 0.868:0.853 0.370 0.542
rs2071429 A 0.563:0.557 0.035 0.851
rs2230037 A 0.405:0.403 0.003 0.958
  rs4898389 A 0.556:0.528 0.607 0.436
  rs5986877 C 0.549:0.524 0.514 0.473
  rs7879049 A 0.608:0.576 0.850 0.356
  rs7053878 T 0.883:0.841 2.847 0.091
  1. Comparison of the genotypes of the 9 polymorphic SNPs with MAF > 10%; frequencies of the associated allele of (Group A)/ (Group B) individuals are also mentioned. Males and females were compared separately using chi squared test.