Malaria Journal

Table 3 Haplotype frequencies

From: G6PD gene variants and its association with malaria in a Sri Lankan population

Block 1	SNPs		Frequency of the haplotype
	rs915941	rs915942	population	Group A	Group B	Males	Females	Males	Group B
						Group A	Group A	Group B	Females
Haplotypes	A	G	0.880	0.890	0.870	-	0.870	0.878	0.871
Haplotypes	C	A	0.119	0.110	0.124	-	0.120	0.122	0.126
Block 2	SNPs					Frequency of the haplotype
	rs2071429	rs2230037	rs4898389	rs5986877	rs7879049	Population (0.64)	Group A (0.73)	Group B (0.77)	Males Group A (N/R)	Females Group A (0.77)	Males Group B (0.76)	Females Group B (0.48)
Haplotypes	A	G	A	C	A	0.545	0.553	0.540	0.475	0.540	0.585	0.516
	G	A	G	G	G	0.402	0.394	0.407	0.475	0.365	0.364	0.431
	G	G	G	G	A	0.034	0.033	0.034	0.013	0.041	0.028	0.038

Population frequencies of the G6PD haplotypes (>1%) are presented with the minor alleles of each SNP is italicized. Haplotype analysis was conducted for the five markers with the alternate allele, in which four were in linkage disequilibrium. The identified haplotype blocks for the entire population, Group A, Group B, Males/ Females in Group A and B are tabulated below. Recombination rates of the two haplotype blocks are indicated within brackets (N/R = Not Relevant).

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ISSN: 1475-2875

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