Cytokine and chemokine profile of the innate and adaptive immune response of schistosoma haematobium and plasmodium falciparum single and co-infected school-aged children from an endemic area of Lambaréné, Gabon

Table 1 Characteristics of the study subjects divided by infection status

	*S.h* -/ *P.f* -	*S.h* +/ *P.f* -	*S.h* -/ *P.f* +	*S.h* +/ *P.f* +	p-value
Number of subjects (%)	28 (22%)	31 (25%)	34 (27%)	32 (26%)	-
Gender: M/F	14/14	13/18	19/15	18/14	0.63
Age in years: Median (IQR)	11 (3.25)	11(5)	9.5(4)	13(3)	0.02
Weight in kgs: Median(IQR)	31.5(12.25)	35(15)	30(9.8)	36(18.25)	0.05
Haemoglobin in g/dl: Median (IQR)	11.9(0.8)	12.25(0.95)	11.1(1.08)	11.8(1.6)	0.003
Number of subjects living in the village for more than 5 years (%)	17(61%)	21(75%)	15(44%)	19(61%)	0.10
Number of filaria infected subjects (%)	2(7%)	4(13%)	2(6%)	2(6%)	0.67
Number of subjects previously treated for S. haematobium: (%)	9(32%)	21(41%)	7(21%)	14(45%)	0.16
S. haematobium eggs count per 10 ml: Median (IQR)	0	15(49.5)	0	52.5(88.5)	0.26^#
P. falciparum CT value Median (IQR)	0	0	28.9 (7.3)	30.7 (8.6)	0.25^#

S.h-/ P.f- : Subjects not infected by either S. haematobium or P. falciparum. S.h+/ P.f-: Subjects with single S. haematobium infection. S.h-/ P.f+: Subjects with single P. falciparum infection. S.h+/ P.f+: S. haematobium and P. falciparum co-infected subjects. M: male and F: female. CT value represents the value of the cycle threshold.
^#p-value computed to compare infected subjects only.

ISSN: 1475-2875