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Table 4 RDT performance compared with matching microscopy and qPCR (n = 415) for all infections regardless of parasite density

From: Comparison of rapid diagnostic test Plasmotec Malaria-3, microscopy, and quantitative real-time PCR for diagnoses of Plasmodium falciparum and Plasmodium vivax infections in Mimika Regency, Papua, Indonesia

RDT performance Plasmodium falciparum (n = 88 microscopy +) Plasmodium vivax (n = 85 microscopy +) Plasmodium falciparum (n = 88 qPCR +) Plasmodium vivax (n = 94 qPCR +)
Prevalence 21.2% 20.5% 21.2% 22.6%
Sn* 92% (84.3-96.7%) 72.9% (62.2-82%) 92% (84.3-96.7%) 66% (55.5-75.4%)
Sp* 96.6% (94.1-98.3%) 99.1% (97.4-99.8%) 96.6% (94.1-98.3%) 99.1% (97.3-99.8%)
PPV* 88% (79.6-93.9%) 95.4% (87.1-99%) 88% (79.6-93.9%) 95.4% (87.1-99.0%)
NPV* 97.8% (95.6-99.1%) 93.4% (90.3-95.8%) 97.8% (95.6-99.1%) 90.9% (87.3-93.7%)
PLR* 27.4 (15.3-49.1) 80.2 (25.8-249) 27.4 (15.3-49.1) 70.6 (22.7-220)
NLR* 0.08 (0.04-0.17) 0.27 (0.19-0.39) 0.08 (0.04-0.17) 0.34 (0.26-0.46)
Kappa 0.87 0.79 0.87 0.73
  1. Sn = sensitivity; Sp = specificity; PPV = positive predictive value; NPV = negative predictive value; PLR = positive likelihood ratio; NLR = negative likelihood ratio.
  2. *95% CI.