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Table 2 Timeline of procedures

From: Screening for an ivermectin slow-release formulation suitable for malaria vector control

Intervention

Weeks

 

0

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

25

Implantation

 

                        

Check up

Vital signs

          

           

 

ECG

          

           

 

Ophthalmoscopy

           

           

 

Toxicology samples

          

           

 

IVM PK samples

 

   

   

   

 

Interim analysis

             

            

Euthanasia (1/2F, 1/2M, 1X)

              

           

Euthanasia (3F, 3M, 2/3X)

                         

  1. IVM: ivermectin; PK: pharmacokinetics.