Table 4 Statistic comparison of area under the curve and likelihood of maintaining plasma levels above 7 ng/ml for 12 weeks

AUC at 12 weeks vs DOC% (ANOVA)

F = 1.98

0.16

AUC at 12 weeks vs surface (ANOVA)

F = 12.37

<0.01

12 weeks over 7 ng/ml vs DOC%

Chi square = 0.37

0.86

12 weeks over 7 ng/ml vs surface

Chi square = 20.55

<0.01