Figure 4From: Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres Effect of number of mosquito bites on pre-patent period. Published data are from 44 volunteers bitten by 1–7 infected mosquitoes at one centre (Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands) [26]. Observed values are given as grey dots with size representing weight. A Loess smooth is displayed with the estimate (black line) and 95% confidence interval (grey ribbon).Back to article page