G6PD deficiency in male individuals infected by Plasmodium vivax malaria in the Brazilian Amazon: a cost study

Malaria Journal

Table 1 Epidemiological parameters in the Brazilian Amazon, 2009, 2010 and 2011

Items	Years
Items	2009	2010	2011	Sources
Number of males submitted to thick blood smear test in Brazilian Amazon¹	1,596,725	1,643,714	1,781,812	[8]
Number of males with G6PDd submitted to thick blood smear test in Brazilian Amazon²	71,853	73,967	80,182	[8] and [9]
Number of males submitted to thick blood smear test in Brazilian Amazon by active demand³	878,473	903,808	968,145	[8]
Number of males with G6PDd submitted to thick blood smear test in Brazilian Amazon by active demand⁴	39,531	40,671	43,567	[8,9]
Number of vivax malaria cases among males	155,413	173,559	141,803	[8]
Number of males with G6PDd among those diagnosed with P. vivax ⁵	6,994	7,810	6,381	[8,9]
Number of units that diagnosed cases of vivax malaria	1,814	1,797	1,639	[8]
Number of municipalities in Brazilian Amazon that reported cases of vivax malaria among men	524	511	472	[8]
Number of males hospitalized with G6PDd after treatment with PQ⁶	6,594	7,364	6,016	[8-10]
Number of deaths attributed to the use of PQ among carrier men of G6PDd ⁷	189	211	172	[8-10]

¹Number estimated from multiplying the total number of people of both genders, subject to examination, by the proportion of males.
²Number estimated from the number of males submitted to thick blood smear examination in Brazilian Amazon weighted by prevalence of G6PDd for males (4.5%).
³Number obtained from multiplying the estimate of males submitted to thick blood smear test by the overall proportion of individuals diagnosed by active demand.
⁴Number estimated from multiplying the number of males submitted to thick blood smear test in Brazilian Amazon by active demand weighted by the prevalence of G6PDd for males (4.5%).
⁵Number estimated from the total cases of P. vivax malaria among males in Brazilian Amazon weighted by prevalence of G6PDd for males (4.5%).
⁶Number estimated from the number of males with G6PDd among those diagnosed with P. vivax multiplied by the proportion of hospitalizations (94.29%) among males with G6PDd monitored from 2009 to 2011 in the FMT-HVD.
⁷Number estimated from the number of males hospitalized with G6PDd after treatment with PQ, multiplied by the proportion of deaths (2.86%) among the bearers of the deficiency monitored in the FMT-HVD.

ISSN: 1475-2875